Miles Morales catapults across the Multiverse, where he encounters a team of Spider-People charged with protecting its very existence. When the heroes clash on how to handle a new threat, Miles must redefine what it means to be a hero. Miles Morales returns for the next chapter of the Oscar®-winning Spider-Verse saga, an epic adventure that will transport Brooklyn's full-time, friendly neighborhood Spider-Man across the Multiverse to join forces with Gwen Stacy and a new team of Spider-People to face off with a villain more powerful than anything they have ever encountered
Chapter 1 On Earth-65 in New York City
over a year after helping defeat Kingpin with Miles Morales, Gwen Stacy relates her struggle to create relationships with anyone around her, feeling isolated in her role as Spider-Woman. After quitting her band, she remembers the last person she felt close to, her best friend Peter Parker. He, along with his Aunt May, was very close to Gwen and her father, Police Captain George Stacy, though she never told any of them about her double life as a superhero. Peter was bullied relentlessly at school, despite Gwen trying to defend him.
Unbeknownst to her, he started experimenting with a dangerous chemical. The night of prom, a giant lizard monster attacked the school and tried to kill Peter's bully. Gwen, leaping into action as Spider-Woman, fought him off, causing the building to collapse on top of the creature. The lizard reverted to Peter, who was mortally injured by the rubble. Gwen tried to save him, but it was too late. Peter revealed he knew she was Spider-Woman, and reassured her before dying in her arms.
Captain Stacy found her over Peter's body and assumed the masked vigilante murdered him, ordering a city-wide manhunt for Spider-Woman. In the present, Gwen returns home to find her dad, who is still determined to bring down the "killer" of his daughter's best friend. Despite Gwen telling him it's no good, he soon leaves to respond to a disturbance at the Guggenheim Museum. Gwen is soon behind him as Spider-Woman, neutralizing the cops outside and entering to find a parchment-based version of the Vulture has been sucked into her dimension and is wreaking havoc inside. She is pinned down by the villain, but is saved by another inter-dimensional traveler, Miguel O'Hara, a.k.a. Spider-Man 2099, leader of the Spider Society. He tells her that Vulture, and others like him, have been getting sucked into alternate universes ever since the collider incident in Miles' world. His suit and powers are still struggling to subdue the Renaissance Era Vulture, and he uses his artificial intelligence called Lyla to call for backup in the form of Jessica Drew, another Spider-Woman. Together, the three are able to stop Vulture and save the civilians and cops in the area, though Miguel nearly uses a pair of hidden fangs on the creature. Gwen is out of web and injured, and stops to rest. She is found and cornered by Captain Stacy, who tries to take her in. With no other options, she reveals her identity as his own daughter, to his shock. Despite her trying to reason with him and proclaim her innocence of Peter's death, he continues to place her under arrest